Brucella Abortus Vaccine (ST19).
DESRIPTION: 
 Freeze dried Brucella Abortus Strain “19” bacteria for the prevantion of brucellosis (contagious abortion ) in cattle and buffalos. 
COMPOSITION:
 Each dose of reconstituted vaccine contains 3-10 x109 CFU of Brucella abortus Strain "19". 
PACKAGE : 
 
 Vials 10 ml contains 10 reduced doses of lyophilized vaccine
 ( 3-10 x 109 CFU / dose ) accompanied with 20 ml diluent .
 INDICATIONS AND DOSAGE :
 
 After reconstitution with the accompanied diluent, it should contain ( 3-10 x 109 CFU ) viable organisms per 2 ml dose,given subcutaneously to female calves between 3 to 8 months old . 
This dose level produces smaller serological responses in calves. Cattle over the age of 8 months may not be vaccinated against brucellosis except with the written approval of a state veterinarian . Cows in advanced pregnancy may abort if vaccinated ,but abortion rate may be only about 1% . 
ADVERSE REACTIONS : 
 These occur rarely in native breeds of both calves and adults and it is more sever in foreign breeds. 
 * A local swelling occurs particularly in adult cattle and there 
 may be a sever systemic reaction manifested by fever lasting 
 for 2-3 days. 
 * Anaphylactic shock may occur and immediate treatment with 
 adrenaline hydrochloride ( 1m1. of 1 : 1000 diluted solution 
 injected subcutaneously ) or Antihistaminic drug, is also 
 recommended . 
STORAGE AND EXPIRY DATE : 
 Living lyophilized Br. Abortus strain ” 19” vaccine should be stored in a dry place protected from light at a temperature between 4 - 8 oC . The vaccine is valid for one year from the manufacture date. 
PRECAUTIONS : 
 * The vaccine must be kept under refrigeration at all times, 
 reconstituted only when required . 
 * It must be used in an aseptic manner to avoid its 
 contamination with other bacteria. 
 * Avoid accedental infection to human during the use of the 
 vaccine. 
 * The product is for animal use only and should not be used for 
 human .
 * Empty and unused open vials and used 
 syringes must be disposed hygienically .
WITHD RAWAL PERIOD : 
 Twenty-on day before human consumption