NewCastle Vaccine (Hitchner B1).
 
COMPOSITION : 
 Freeze dried pellet with a minimum content of 106 EID50 per field dose of Newcastle Disease Virus, HitchnerB1 propagated on SPF embryonated chicken eggs .
INDICATIONS : 
 Newcastle vaccine Hitchner B1 is used for prophylactic immunization of healthy chicks and adult birds of fowls, turkeys and game birds against Newcastle Disease.
 The vaccine is safe and is used for primary vaccination of newly hatched chickens and for booster vaccinations in older birds. 
METHOD OF ADMINISTRATION : 
 
 The vaccine can be given by eye dropping, in the drinking water or by spraying.
EYE DROPPING :
 Dissolve 1000 doses of vaccine in 30 ml of sterile physiological saline. Apply a drop to one open eye of each bird from a distance of half inch. The dropper used should be designed to give 0.03 ml per drop. The diluent used (Sterile normal saline) should be at body temperature of the birds.
DRINKING WATER :
 1) The birds should be deprived drinking water for at least 4 
 hours before vaccination. 
 2) The vaccine solution is prepared just at the time of use. For 
 best results the drinking water used should be relatively 
 cold and in such a quantity that will be drink within less 
 than two hours. 
 3) The 1000 doses vial is dissolved in distilled water or pure 
 unchlorinated tap water in the following dilutions 
 according to the age as follows :
 1st week in 5 liters
 chicken 1-4 weeks in 10 liters
 chicken 1-4 weeks in 20 liters
 over 10 weeks in 40 liters
NOTE :
 a) The water troughs used for drinking water vaccination should 
 be free from chlorine, quaternary ammonium compounds or 
 other drinking water sanitizers or disinfectants. 
 b) Metalic water troughs should be avoided.
 c) Ensure that there is enough drinking trough space to allow all 
 birds immediate access to the vaccine.
 
 d) The vaccine is administered during the cooler hours of the 
 day, and it must be kept away from any source of heat and 
 sun light. 
 e) Dried milk or skimmed milk may be added to drinking water 
 (1kg to 400 liters) to protect the vaccine . 
 SPRAYING:
 1) Dissolve the vial of 1000 doses in sterile physiological saline 
 solution in the following rate according to age as follows :
 1st to 4th week 100 ml
 After the 4th week 200 ml
 Adult birds 400 ml 
 2) Spray the vaccine solution at a distance of about 1 metre 
 using a pressure spray which produces droplets of 5 – 20 
 microns in diameter,
 3) During spraying it is advisable to protect eyes and nostrils, 
 e.g. by a face mask to avoid allergies of N.D. infection. 
NOTE :
 
· Healthy birds with no previous history of respiratory infection 
 should \ only be vaccinated by spraying.
· To ensure proper administration only approved sprayers should be used.
STORAGE : 
 
 Store between 4 - 8 oC or in the freezer at -20oC. 
PACKAGE : 
 Vial of 1000 doses. 
EXPIRY DATE : 
 
 Two years from the date of manufacture at 4 – 8 oC. 
 Three years from the date of manufacture at -20 oC .
WITHDRAW PERIOD:
 Twenty one days stop the vaccination before human consumption.